deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT05856331

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema (ELEVAATE)

Phase 2, Double-Blind, Randomized, Active-Control, Parallel Group Study to Assess the Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Safety of SAR447537 (INBRX-101) Compared to Plasma-Derived Alpha1-Proteinase Inhibitor (A1PI) Augmentation Therapy in Adults With Alpha-1 Antitrypsin Deficiency (AATD) Emphysema

Sponsor: Sanofi

Updated 18 times since 2023 Last updated: Aug 8, 2025 Started: Oct 12, 2023 Primary completion: Aug 6, 2025 Completion: Aug 6, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Alpha 1-Antitrypsin Deficiency and Emphysema, this trial is completed. The trial is conducted by Sanofi and has accumulated 18 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

18 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Feb 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

Show 13 earlier versions
  1. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  3. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE2

  4. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE2

  5. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE2

  6. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE2

  7. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  8. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

  9. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

  10. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  11. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  12. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  13. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .