Recruiting PHASE1 INTERVENTIONAL 2-arm NCT05862012

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

A Phase 1, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 2001 in Subjects With Relapsed/Refractory Multiple Myeloma

Sponsor: Ichnos Sciences SA

Conditions Relapsed/Refractory Multiple Myeloma

Interventions ISB 2001

Updated 9 times since 2023 Last updated: Mar 11, 2026 Started: Nov 1, 2023 Primary completion: Jul 31, 2027 Completion: Jul 31, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Relapsed/Refractory Multiple Myeloma and is currently actively recruiting participants. Ichnos Sciences SA leads this study, which shows 9 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

9 versions recorded

Mar 2026 — Present [monthly]

Recruiting PHASE1
Oct 2025 — Mar 2026 [monthly]

Recruiting PHASE1
Sep 2025 — Oct 2025 [monthly]

Recruiting PHASE1
Jul 2025 — Sep 2025 [monthly]

Recruiting PHASE1
Jan 2025 — Jul 2025 [monthly]

Recruiting PHASE1

▶ Show 4 earlier versions

Sep 2024 — Jan 2025 [monthly]

Recruiting PHASE1
Aug 2024 — Sep 2024 [monthly]

Recruiting PHASE1
Jul 2024 — Aug 2024 [monthly]

Recruiting PHASE1

Status: Not Yet Recruiting → Recruiting
Jun 2023 — Jul 2024 [monthly]

Not Yet Recruiting PHASE1

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ichnos Sciences SA

Data source: Ichnos Sciences SA

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Bangalore, India , Benowa, Australia , Chapel Hill, United States , Chicago, United States , Concord, Australia , Fitzroy, Australia , Melbourne, Australia , Milwaukee, United States , Nedlands, Australia , Palo Alto, United States and 1 more location