Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05873881

COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease (COLT-HF)

Sponsor: Canadian Institutes of Health Research (CIHR)

Interventions Colchicine 0.5 MG Colchicine placebo Thiamine Mononitrate 300 mg

Updated 6 times since 2023 Last updated: Jun 16, 2025 Started: Jan 29, 2024 Primary completion: Jun 30, 2027 Completion: Jun 30, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Heart Failure, this trial is actively recruiting participants. The trial is conducted by Canadian Institutes of Health Research (CIHR) and has accumulated 6 data snapshots since 2024. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

6 versions recorded

Jul 2025 — Present [monthly]

Recruiting PHASE3
Sep 2024 — Jul 2025 [monthly]

Recruiting PHASE3
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE3
Mar 2024 — Jul 2024 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Oct 2023 — Mar 2024 [monthly]

Not Yet Recruiting PHASE3

▶ Show 1 earlier version

Jun 2023 — Oct 2023 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Canadian Institutes of Health Research (CIHR)
Hamilton Health Sciences Corporation
Population Health Research Institute

Data source: Hamilton Health Sciences Corporation

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Hamilton, Canada