deltatrials
Terminated PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT05889793

Evaluating Emetine for Viral Outbreaks (EVOLVE) (EVOLVE)

Emetine for Viral Outbreaks: Randomized, Double-Blind, Placebo-Controlled, Clinical Trial to Evaluate Oral Emetine Against Covid-19 (EVOLVE)

Sponsor: Bharatpur Hospital Chitwan

Conditions COVID-19
Updated 11 times since 2023 Last updated: Jan 22, 2026 Started: May 15, 2024 Primary completion: Dec 15, 2025 Completion: Dec 15, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated due to insufficient participant enrollment resulting from a lower-than-expected number of COVID-19 cases

A PHASE2/PHASE3 clinical study on COVID-19, this trial is terminated or withdrawn. The trial is conducted by Bharatpur Hospital Chitwan and has accumulated 11 data snapshots since 2024. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshotNot Yet Recruiting~Nov 2023 – ~Feb 2024 · 3 months · monthly snapshotNot Yet Recruiting~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotRecruiting~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshotRecruiting~Feb 2026 – present · 3 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2/PHASE3

    Status: RecruitingTerminated

  2. Jun 2025 — Feb 2026 [monthly]

    Recruiting PHASE2/PHASE3

  3. Sep 2024 — Jun 2025 [monthly]

    Recruiting PHASE2/PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

Show 6 earlier versions
  1. May 2024 — Jun 2024 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  2. Apr 2024 — May 2024 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  3. Feb 2024 — Apr 2024 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  4. Nov 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  5. Aug 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  6. Jul 2023 — Aug 2023 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bharatpur Hospital Chitwan
  • Johns Hopkins University
  • Nepal Health Research Council
  • Rutgers University
  • Stony Brook University
Data source: Johns Hopkins University

For direct contact, visit the study record on ClinicalTrials.gov .