Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05904028

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD (AO)

Sponsor: Jaeb Center for Health Research

Conditions Neovascular Age-related Macular Degeneration

Interventions Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule Intravitreal injections of 6 mg faricimab on a home optical coherence tomography-guided treatment schedule

Updated 17 times since 2023 Last updated: Jan 27, 2026 Started: Nov 9, 2023 Primary completion: Jul 30, 2027 Completion: Jul 30, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Neovascular Age-related Macular Degeneration, this trial is actively recruiting participants. The trial is conducted by Jaeb Center for Health Research and has accumulated 17 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

17 versions recorded

Feb 2026 — Present [monthly]

Recruiting PHASE3
Dec 2025 — Feb 2026 [monthly]

Recruiting PHASE3
Oct 2025 — Dec 2025 [monthly]

Recruiting PHASE3
Sep 2025 — Oct 2025 [monthly]

Recruiting PHASE3
Jul 2025 — Sep 2025 [monthly]

Recruiting PHASE3

▶ Show 12 earlier versions

Jun 2025 — Jul 2025 [monthly]

Recruiting PHASE3
Mar 2025 — Jun 2025 [monthly]

Recruiting PHASE3
Jan 2025 — Mar 2025 [monthly]

Recruiting PHASE3
Oct 2024 — Jan 2025 [monthly]

Recruiting PHASE3
Sep 2024 — Oct 2024 [monthly]

Recruiting PHASE3
Aug 2024 — Sep 2024 [monthly]

Recruiting PHASE3
Jul 2024 — Aug 2024 [monthly]

Recruiting PHASE3
Jun 2024 — Jul 2024 [monthly]

Recruiting PHASE3
Apr 2024 — Jun 2024 [monthly]

Recruiting PHASE3
Mar 2024 — Apr 2024 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Oct 2023 — Mar 2024 [monthly]

Not Yet Recruiting PHASE3
Jul 2023 — Oct 2023 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Jaeb Center for Health Research
Juvenile Diabetes Research Foundation
National Eye Institute (NEI)
National Institutes of Health (NIH)

Data source: Jaeb Center for Health Research

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Augusta, United States , Austin, United States , Ayer, United States , Baltimore, United States , Bellaire, United States , Boston, United States , Cherry Hill, United States , Chicago, United States , Cleveland, United States , Dallas, United States and 43 more locations