deltatrials
Terminated NA INTERVENTIONAL 2-arm NCT05910775

Role Of Non-Specific Effects in The Treatment of Depression With Esketamine (ROSETTE)

Sponsor: National Center for Advancing Translational Sciences (NCATS)

Conditions Depressive Episode
Interventions Pre and Post Treatment Presentations
Updated 11 times since 2023 Last updated: Dec 22, 2025 Started: Jul 13, 2024 Primary completion: Dec 31, 2024 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was suspended due to challenges in recruiting a sufficient number of participants within a reasonable timeframe. Despite our efforts, enrollment did not meet the required threshold to proceed as planned.

Other terminated trials from National Center for Advancing Translational Sciences (NCATS)

See all terminations from National Center for Advancing Translational Sciences (NCATS)

A NA clinical study on Depressive Episode, this trial is terminated or withdrawn. The trial is conducted by National Center for Advancing Translational Sciences (NCATS) and has accumulated 11 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshotNot Yet Recruiting~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Apr 2024 · 3 months · monthly snapshotRecruiting~Apr 2024 – ~Jun 2024 · 2 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotEnrolling By Invitation~Apr 2025 – ~Feb 2026 · 10 months · monthly snapshotTerminated~Feb 2026 – present · 5 months · monthly snapshotTerminated

Change History

11 versions recorded

  1. Feb 2026 — Present [monthly]

    Terminated NA

  2. Apr 2025 — Feb 2026 [monthly]

    Terminated NA

    Status: Enrolling By Invitation → Terminated

  3. Sep 2024 — Apr 2025 [monthly]

    Enrolling By Invitation NA

    Status: Recruiting → Enrolling By Invitation

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting NA

▶ Show 6 earlier versions

  1. Apr 2024 — Jun 2024 [monthly]

    Recruiting NA

  2. Jan 2024 — Apr 2024 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  3. Dec 2023 — Jan 2024 [monthly]

    Not Yet Recruiting NA

  4. Nov 2023 — Dec 2023 [monthly]

    Not Yet Recruiting NA

  5. Aug 2023 — Nov 2023 [monthly]

    Not Yet Recruiting NA

  6. Jul 2023 — Aug 2023 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Center for Advancing Translational Sciences (NCATS)
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations