Active Not Recruiting PHASE4 INTERVENTIONAL 2-arm NCT05944952

Low-dose Versus a High-dose Sublingual Buprenorphine Induction

A Pilot Study Comparing a Low-dose Versus a High-dose Sublingual Buprenorphine Induction Dosing Scheme in Fentanyl Using Patients With Opioid Use Disorder (OUD)

Sponsor: Friends Research Institute, Inc.

Conditions Opioid Use Disorder

Interventions buprenorphine/naloxone

Updated 6 times since 2023 Last updated: Aug 6, 2025 Started: Jun 20, 2024 Primary completion: Dec 31, 2024 Completion: Oct 30, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05944952, this PHASE4 trial focuses on Opioid Use Disorder and remains ongoing. Sponsored by Friends Research Institute, Inc., it has been updated 6 times since 2024, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Active Not Recruiting PHASE4
Apr 2025 — Sep 2025 [monthly]

Active Not Recruiting PHASE4

Status: Recruiting → Active Not Recruiting
Sep 2024 — Apr 2025 [monthly]

Recruiting PHASE4
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE4
Mar 2024 — Jul 2024 [monthly]

Recruiting PHASE4

Status: Not Yet Recruiting → Recruiting

▶ Show 1 earlier version

Aug 2023 — Mar 2024 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Friends Research Institute, Inc.
MATClinics

Data source: Friends Research Institute, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Dundalk, United States