deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05983250

LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF (LEVEL)

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

Sponsor: Medpace, Inc.

Interventions Placebo TNX-103
Updated 16 times since 2023 Last updated: Feb 13, 2026 Started: Jan 10, 2024 Primary completion: Oct 31, 2026 Completion: Oct 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05983250, this PHASE3 trial focuses on Pulmonary Hypertension and remains actively recruiting participants. Sponsored by Medpace, Inc., it has been updated 16 times since 2024, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshotNot Yet Recruiting~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Apr 2025 · 5 months · monthly snapshotRecruiting~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshotRecruiting~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshotRecruiting~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshotRecruiting

Change History

16 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE3

  2. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE3

  3. Sep 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

  4. Apr 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  5. Nov 2024 — Apr 2025 [monthly]

    Recruiting PHASE3

Show 11 earlier versions
  1. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  2. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  3. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  6. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  7. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE3

  8. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

  9. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  10. Oct 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE3

  11. Sep 2023 — Oct 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Medpace, Inc.
  • Northwestern University
  • Tenax Therapeutics, Inc.
Data source: Tenax Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .