deltatrials
Recruiting INTERVENTIONAL NCT05997381

BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears (REinForce)

REinForce: A Prospective, Single Blind, Multi-Center, Randomized, Controlled, Pivotal Study to Evaluate the Safety and Effectiveness of the BioBrace® Implant During Arthroscopic Repair of Full Thickness Rotator Cuff Tears

Sponsor: CONMED Corporation

Updated 11 times since 2023 Last updated: Apr 20, 2026 Started: Jan 5, 2024 Primary completion: Dec 1, 2026 Completion: Jun 1, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Rotator Cuff Tears and is currently actively recruiting participants. CONMED Corporation leads this study, which shows 11 recorded versions since 2024 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Study Description(click to expand)

This is a prospective, single blind, multi-center, randomized, controlled, pivotal clinical study investigating the treatment of full thickness tears of the rotator cuff. Tears must involve the supraspinatus and/or infraspinatus tendons and measure ≥ 2 cm and \< 5 cm. Subjects meeting the inclusion/exclusion criteria will be enrolled and will undergo either arthroscopic rotator cuff repair augmented with the BioBrace® Implant or arthroscopic rotator cuff repair alone. Clinical evaluations will be conducted at baseline (pre-operatively) and at 6 weeks, 3-, 6-, and 12-months post-operatively using various patient-reported outcome measures and MRI to assess repair integrity and re-tear rate.

This is a prospective, single blind, multi-center, randomized, controlled, pivotal clinical study investigating the treatment of full thickness tears of the rotator cuff. Tears must involve the supraspinatus and/or infraspinatus tendons and measure ≥ 2 cm and \< 5 cm. Subjects meeting the inclusion/exclusion criteria will be enrolled and will undergo either arthroscopic rotator cuff repair augmented with the BioBrace® Implant or arthroscopic rotator cuff repair alone. Clinical evaluations will be conducted at baseline (pre-operatively) and at 6 weeks, 3-, 6-, and 12-months post-operatively using various patient-reported outcome measures and MRI to assess repair integrity and re-tear rate.

Status Flow

~Sep 2023 – ~Feb 2024 · 5 months · monthly snapshotNot Yet Recruiting~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotEnrolling By Invitation~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotEnrolling By Invitation~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotEnrolling By Invitation~Jan 2025 – ~Aug 2025 · 7 months · monthly snapshotEnrolling By Invitation~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshotEnrolling By Invitation~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshotEnrolling By Invitation~Oct 2025 – ~Apr 2026 · 6 months · monthly snapshotRecruitingApr 16, 2026 – Apr 28, 2026 · 12 days · daily APIRecruitingApr 28, 2026 – present · 2 months · daily APIRecruiting

Change History

11 versions recorded
  1. Apr 28, 2026 — Present [daily]

    Recruiting

  2. Apr 16, 2026 — Apr 28, 2026 [daily]

    Recruiting

    Phase: NANone

  3. Oct 2025 — Apr 2026 [monthly]

    Recruiting NA

    Status: Enrolling By InvitationRecruiting

  4. Sep 2025 — Oct 2025 [monthly]

    Enrolling By Invitation NA

  5. Aug 2025 — Sep 2025 [monthly]

    Enrolling By Invitation NA

Show 6 earlier versions
  1. Jan 2025 — Aug 2025 [monthly]

    Enrolling By Invitation NA

  2. Sep 2024 — Jan 2025 [monthly]

    Enrolling By Invitation NA

  3. Jul 2024 — Sep 2024 [monthly]

    Enrolling By Invitation NA

  4. Jun 2024 — Jul 2024 [monthly]

    Enrolling By Invitation NA

    Status: RecruitingEnrolling By Invitation

  5. Feb 2024 — Jun 2024 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  6. Sep 2023 — Feb 2024 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

This study aims to evaluate the safety and effectiveness of arthroscopic rotator cuff repair augmented with the BioBrace® Implant vs. arthroscopic rotator cuff repair alone in subjects requiring surgical intervention for a full-thickness rotator cuff tear.

Contact Information

Sponsor contact:
  • CONMED Corporation
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations