Recruiting PHASE2 INTERVENTIONAL 5-arm NCT06019130

Nivolumab in Children and Adults With Nasopharyngeal Carcinoma (NPC-Nivo)

Nivolumab in Combination With Cisplatin and 5-Fluorouracil as Induction Therapy in Children and Adults With EBV-positive Nasopharyngeal Carcinoma

Sponsor: Deutsche Krebshilfe e.V., Bonn (Germany)

Conditions Nasopharyngeal Cancer Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms Nasopharynx Cancer

Interventions 5-Fluorouracil Cisplatin Gemcitabine Interferon beta-1a MRI Nivolumab PET Patient-Reported Outcomes Radiotherapy

Updated 5 times since 2023 Last updated: May 14, 2024 Started: Jan 10, 2023 Primary completion: Jan 9, 2026 Completion: Jan 9, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06019130, this PHASE2 trial focuses on Nasopharyngeal Cancer and Nasopharyngeal Carcinoma and remains actively recruiting participants. Sponsored by Deutsche Krebshilfe e.V., Bonn (Germany), it has been updated 5 times since 2023, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

5 versions recorded

Sep 2025 — Present [monthly]

Recruiting PHASE2
Sep 2024 — Sep 2025 [monthly]

Recruiting PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE2
Jun 2024 — Jul 2024 [monthly]

Recruiting PHASE2
Sep 2023 — Jun 2024 [monthly]

Recruiting PHASE2

First recorded

Jan 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Deutsche Krebshilfe e.V., Bonn (Germany)
German Society for Pediatric Oncology and Hematology GPOH gGmbH

Data source: German Society for Pediatric Oncology and Hematology GPOH gGmbH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Berlin, Germany , Bielefeld, Germany , Bonn, Germany , Cologne, Germany , Cottbus, Germany , Dortmund, Germany , Dresden, Germany , Erlangen, Germany , Essen, Germany and 16 more locations