Recruiting PHASE3 INTERVENTIONAL 3-arm NCT06027099

CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial

Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Spine Surgery

Sponsor: Stanford University

Conditions Back Pain Chronic Pain Neck Pain Opioid Misuse

Interventions Enhanced Usual Care MI-Opioid Taper Placebo Tizanidine

Updated 4 times since 2023 Last updated: Sep 26, 2025 Started: Dec 5, 2024 Primary completion: Jan 31, 2028 Completion: Jul 31, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Back Pain and Chronic Pain and is currently actively recruiting participants. Stanford University leads this study, which shows 4 recorded versions since 2024 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

4 versions recorded

Oct 2025 — Present [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Sep 2024 — Oct 2025 [monthly]

Not Yet Recruiting PHASE3
Jul 2024 — Sep 2024 [monthly]

Not Yet Recruiting PHASE3
Oct 2023 — Jul 2024 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Stanford University

Data source: Stanford University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Stanford, United States