deltatrials
Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06057935

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

ICARuS II (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Multicenter, Randomized Phase II Trial of Normothermic Intraperitoneal Chemotherapy and Intravenous Chemotherapy After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Malignant Peritoneal Mesothelioma

Sponsor: Memorial Sloan Kettering Cancer Center

Updated 9 times since 2023 Last updated: Jul 17, 2025 Started: Sep 21, 2023 Primary completion: Sep 21, 2028 Completion: Sep 21, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06057935, this PHASE2 trial focuses on Malignant Mesothelioma and Malignant Peritoneal Mesothelioma and remains actively recruiting participants. Sponsored by Memorial Sloan Kettering Cancer Center, it has been updated 9 times since 2023, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Oct 2023 – ~May 2024 · 7 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Jun 2025 · 7 months · monthly snapshotRecruiting~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshotRecruiting

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Recruiting PHASE2

  2. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  3. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

  4. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE2

  5. Nov 2024 — Jun 2025 [monthly]

    Recruiting PHASE2

Show 4 earlier versions
  1. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  3. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  4. Oct 2023 — May 2024 [monthly]

    Recruiting PHASE2

    First recorded

Sep 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .