Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06072898

A Randomized Neuroimaging Trial of Psilocybin in Depression (EMBRACE)

Engaging Mood Brain Circuits With Psilocybin: a Randomized Neuroimaging Trial in Depression

Sponsor: Sunnybrook Health Sciences Centre

Conditions Depressive Disorder Major Depressive Disorder

Interventions Microcrystalline cellulose Psilocybin Supportive psychotherapy

Updated 7 times since 2023 Last updated: Jun 8, 2025 Started: Mar 25, 2025 Primary completion: Jun 30, 2027 Completion: Jun 30, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Depressive Disorder and Major Depressive Disorder, this trial is actively recruiting participants. The trial is conducted by Sunnybrook Health Sciences Centre and has accumulated 7 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

7 versions recorded

Jul 2025 — Present [monthly]

Recruiting PHASE2
Jun 2025 — Jul 2025 [monthly]

Recruiting PHASE2
Apr 2025 — Jun 2025 [monthly]

Recruiting PHASE2

Status: Not Yet Recruiting → Recruiting
Sep 2024 — Apr 2025 [monthly]

Not Yet Recruiting PHASE2
Jul 2024 — Sep 2024 [monthly]

Not Yet Recruiting PHASE2

▶ Show 2 earlier versions

May 2024 — Jul 2024 [monthly]

Not Yet Recruiting PHASE2
Nov 2023 — May 2024 [monthly]

Not Yet Recruiting PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Sunnybrook Health Sciences Centre

Data source: Sunnybrook Health Sciences Centre

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Toronto, Canada