deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT06118086

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

A Phase 1/2, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

Sponsor: Remix Therapeutics

Interventions REM-422
Updated 11 times since 2023 Last updated: Feb 13, 2026 Started: Dec 20, 2023 Primary completion: Jun 1, 2026 Completion: Jun 1, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Adenoid Cystic Carcinoma and Metastatic Adenoid Cystic Carcinoma and is currently actively recruiting participants. Remix Therapeutics leads this study, which shows 11 recorded versions since 2023 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotRecruiting~Dec 2024 – ~May 2025 · 5 months · monthly snapshotRecruiting~May 2025 – ~Sep 2025 · 4 months · monthly snapshotRecruiting~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshotRecruiting~Feb 2026 – present · 7 months · monthly snapshotRecruiting

Change History

11 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1PHASE1/PHASE2

  2. Nov 2025 — Feb 2026 [monthly]

    Recruiting PHASE1

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  4. May 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  5. Dec 2024 — May 2025 [monthly]

    Recruiting PHASE1

Show 6 earlier versions
  1. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  4. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Feb 2024 — May 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  6. Dec 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Remix Therapeutics
Data source: Remix Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .