deltatrials
Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06137378

European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] (ELOS)

ELOS - Induction Chemotherapy With Docetaxel and Cisplatin Followed by Radiation Compared to Additional PD-1 Inhibition in CPS ≥1 Advanced Laryngeal/Hypopharyngeal Cancer Suitable for Laryngectomy Selected After Early Response Evaluation

Sponsor: Ernst von Bergmann Hospital

Interventions KEYTRUDA®
Updated 5 times since 2023 Last updated: Sep 18, 2024 Started: Apr 17, 2024 Primary completion: Dec 31, 2028 Completion: Dec 31, 2030
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06137378, this PHASE2 trial focuses on Hypopharyngeal Squamous Cell Carcinoma and Laryngeal Cancer and remains actively recruiting participants. Sponsored by Ernst von Bergmann Hospital, it has been updated 5 times since 2024, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Sep 2025 · 11 months · monthly snapshotRecruiting~Sep 2025 – present · 10 months · monthly snapshotRecruiting

Change History

5 versions recorded
  1. Sep 2025 — Present [monthly]

    Recruiting PHASE2

  2. Oct 2024 — Sep 2025 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Sep 2024 — Oct 2024 [monthly]

    Not Yet Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE2

  5. Dec 2023 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ernst von Bergmann Hospital
  • Technical University of Munich
  • University of Cologne
  • University of Göttingen
  • University of Jena
  • University of Kiel
  • University of Leipzig
  • University of Regensburg
  • University of Ulm
  • Universitätsmedizin Mannheim
  • Wuerzburg University Hospital
Data source: University of Leipzig

For direct contact, visit the study record on ClinicalTrials.gov .