Unknown PHASE4 INTERVENTIONAL 2-arm NCT06184113

Apixaban for the Prevention of Latent Biological Valve Thrombosis

Comparison of Apixaban and Aspirin for the Prevention of Latent Bioprosthetic Valve Thrombosis After Aortic Valve Replacement Surgery: Study Protocol for a Prospective Randomized Trial

Sponsor: Clinical Hospital Centre Zagreb

Conditions Antithrombotic Therapy Aortic Valve Replacement Bioprosthetic Valve Thrombosis Rapid Deployment Valves

Interventions Aortic valve replacement surgery Computed tomography Echocardiography

Updated 5 times since 2024 Last updated: Dec 29, 2023 Started: Dec 31, 2023 Primary completion: Dec 31, 2025 Completion: Dec 31, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Antithrombotic Therapy and Aortic Valve Replacement and is currently ongoing. Clinical Hospital Centre Zagreb leads this study, which shows 5 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

5 versions recorded

Feb 2026 — Present [monthly]

Unknown PHASE4

Status: Recruiting → Unknown
Sep 2024 — Feb 2026 [monthly]

Recruiting PHASE4
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE4
Feb 2024 — Jul 2024 [monthly]

Recruiting PHASE4
Jan 2024 — Feb 2024 [monthly]

Recruiting PHASE4

First recorded

Dec 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Clinical Hospital Centre Zagreb

Data source: Clinical Hospital Centre Zagreb

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Zagreb, Croatia