deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT06221371

Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion (TNK-PLUS)

Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion: a Multi-center, Prospective, Randomized, Open-label, Blinded Endpoint (PROBE), Phase 3 Trial

Sponsor: Beijing Tiantan Hospital

Updated 5 times since 2024 Last updated: Nov 21, 2025 Started: Jan 25, 2024 Primary completion: Oct 13, 2025 Completion: Oct 13, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Endovascular Treatment and Ischemic Stroke, Acute, this trial is completed. The trial is conducted by Beijing Tiantan Hospital and has accumulated 5 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshotActive Not Recruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2025 · 15 months · monthly snapshotRecruiting~Dec 2025 – present · 7 months · monthly snapshotCompleted

Change History

5 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE3

    Status: RecruitingCompleted

  2. Sep 2024 — Dec 2025 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  5. Feb 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Jan 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Beijing Tiantan Hospital
  • Linyi People's Hospital
Data source: Beijing Tiantan Hospital

For direct contact, visit the study record on ClinicalTrials.gov .