Completed PHASE2 INTERVENTIONAL 4-arm NCT06237049

A Study to Learn About a Combined COVID-19 and Influenza Shot in Healthy Adults

A Phase 1/2 Randomized Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Modified RNA COVID-19 Vaccine and a Recombinant Influenza Vaccine Administered as a Single Injection in Healthy Adults 50 Years of Age or Older

Sponsor: Pfizer

Conditions COVID-19 Influenza, Human SARS-CoV-2 Infection

Interventions BNT162b2 (Omi XBB.1.5) BNT162b2 (Omi XBB.1.5)/RIV Normal saline placebo RIV

Updated 9 times since 2024 Last updated: Sep 9, 2025 Started: Jan 31, 2024 Primary completion: Sep 13, 2024 Completion: Sep 13, 2024

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on COVID-19 and Influenza, Human, this trial is completed. The trial is conducted by Pfizer and has accumulated 9 data snapshots since 2024. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

Change History

9 versions recorded

Oct 2025 — Present [monthly]

Completed PHASE2
Sep 2025 — Oct 2025 [monthly]

Completed PHASE2
Nov 2024 — Sep 2025 [monthly]

Completed PHASE2

Status: Active Not Recruiting → Completed
Oct 2024 — Nov 2024 [monthly]

Active Not Recruiting PHASE2
Sep 2024 — Oct 2024 [monthly]

Active Not Recruiting PHASE2

▶ Show 4 earlier versions

Aug 2024 — Sep 2024 [monthly]

Active Not Recruiting PHASE2
Jul 2024 — Aug 2024 [monthly]

Active Not Recruiting PHASE2
Apr 2024 — Jul 2024 [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting
Mar 2024 — Apr 2024 [monthly]

Recruiting PHASE2

First recorded

Jan 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Pfizer

Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlantis, United States , Charlottesville, United States , Columbus, United States , Hialeah, United States , Honolulu, United States , Houston, United States , Lake Forest, United States , Las Vegas, United States , Melbourne, United States , Mesquite, United States and 15 more locations