deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT06252285

Efficacy, Immunogenicity, and Safety Study of a Respiratory Syncytial Virus Vaccine in Infants and Toddlers (PEARL)

Phase III, Randomized, Observer-blind, Placebo-controlled, Multi-center, Multinational Study to Evaluate the Efficacy, Immunogenicity, and Safety of a Respiratory Syncytial Virus Vaccine in Infants and Toddlers (PEARL)

Sponsor: Sanofi Pasteur, a Sanofi Company

Updated 10 times since 2024 Last updated: Jan 30, 2026 Started: Feb 6, 2024 Primary completion: Dec 4, 2025 Completion: Dec 4, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision

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This PHASE3 trial investigates RSV Immunisation and is currently terminated or withdrawn. Sanofi Pasteur, a Sanofi Company leads this study, which shows 10 recorded versions since 2024 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshotActive Not Recruiting~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 5 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE3

    Status: Active Not RecruitingTerminated

  2. Sep 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  4. Dec 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

  5. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

Show 5 earlier versions
  1. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  2. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  5. Mar 2024 — Apr 2024 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Feb 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sanofi Pasteur, a Sanofi Company
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .