Recruiting PHASE1/PHASE2 INTERVENTIONAL 6-arm NCT06316297

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

A Phase I/II, Randomized, Placebo-controlled, Multi-arm, Dose-finding Study to Evaluate the Safety, Efficacy and Immunogenicity of an Acne mRNA Vaccine Candidate in Adults With Moderate to Severe Acne 18 to 45 Years of Age

Sponsor: Sanofi Pasteur, a Sanofi Company

Conditions Acne

Interventions Acne mRNA vaccine Placebo

Updated 13 times since 2024 Last updated: Nov 21, 2025 Started: Apr 5, 2024 Primary completion: Aug 31, 2028 Completion: Aug 31, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Acne, this trial is actively recruiting participants. The trial is conducted by Sanofi Pasteur, a Sanofi Company and has accumulated 13 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

13 versions recorded

Dec 2025 — Present [monthly]

Recruiting PHASE1/PHASE2
Nov 2025 — Dec 2025 [monthly]

Recruiting PHASE1/PHASE2
Oct 2025 — Nov 2025 [monthly]

Recruiting PHASE1/PHASE2
Sep 2025 — Oct 2025 [monthly]

Recruiting PHASE1/PHASE2
Jul 2025 — Sep 2025 [monthly]

Recruiting PHASE1/PHASE2

▶ Show 8 earlier versions

Jun 2025 — Jul 2025 [monthly]

Recruiting PHASE1/PHASE2
Mar 2025 — Jun 2025 [monthly]

Recruiting PHASE1/PHASE2
Feb 2025 — Mar 2025 [monthly]

Recruiting PHASE1/PHASE2
Nov 2024 — Feb 2025 [monthly]

Recruiting PHASE1/PHASE2
Sep 2024 — Nov 2024 [monthly]

Recruiting PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
May 2024 — Jul 2024 [monthly]

Recruiting PHASE1_PHASE2
Apr 2024 — May 2024 [monthly]

Recruiting PHASE1_PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Sanofi Pasteur, a Sanofi Company

Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Allen Park, United States , Ames, United States , Barrie, Canada , Baton Rouge, United States , Baytown, United States , Bountiful, United States , Bowling Green, United States , Boynton Beach, United States , Brighton, United States , Camp Hill, United States and 70 more locations