Emergency Medicine Pulmonary Embolism Testing Multicentre Study (EMPET)
Sponsor: Canadian Institutes of Health Research (CIHR)
A observational or N/A phase clinical study on D-dimer and Diagnosis, this trial is actively recruiting participants. The trial is conducted by Canadian Institutes of Health Research (CIHR) and has accumulated 7 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Status Flow
Change History
7 versions recorded-
Apr 16, 2026 — Present [daily]
Recruiting
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Jun 2025 — Apr 2026 [monthly]
Recruiting
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Apr 2025 — Jun 2025 [monthly]
Recruiting
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Nov 2024 — Apr 2025 [monthly]
Recruiting
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Sep 2024 — Nov 2024 [monthly]
Recruiting
▶ Show 2 earlier versions
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Jul 2024 — Sep 2024 [monthly]
Recruiting
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Apr 2024 — Jul 2024 [monthly]
Recruiting
First recorded
Jan 2024
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
It is important to diagnose pulmonary embolism in a timely manner to prevent death and long-term disability. More than half a million people (4-5% of emergency department patients) are tested for pulmonary embolism, although the positive rate is low. Imaging for PE testing exposes patients to radiation, is expensive, adds time to the emergency visit, and can lead to a false positive diagnoses. Existing protocols aimed at reducing unnecessary pulmonary embolism imaging are complex and seldom used by emergency physicians. Too many patients undergo unnecessary pulmonary embolism imaging. A new tool (called Adjust-Unlikely) could safely reduce pulmonary embolism imaging in Canada. A research group composed of researchers, emergency physicians, and patients developed the Adjust-Unlikely clinical decision rule: a rule which has been customized for emergency physicians and emergency patients. Adjust-Unlikely is highly sensitive at the bedside, meaning there are very few false negative results. The study aim is to prospectively validate Adjust-Unlikely pulmonary embolism testing in emergency patients with suspected pulmonary embolism.
Contact Information
- Canadian Institutes of Health Research (CIHR)
- Dr. Kerstin de Wit
For direct contact, visit the study record on ClinicalTrials.gov .