deltatrials
Recruiting OBSERVATIONAL NCT06320236

Emergency Medicine Pulmonary Embolism Testing Multicentre Study (EMPET)

Sponsor: Canadian Institutes of Health Research (CIHR)

Interventions Adjust-Unlikely
Updated 7 times since 2024 Last updated: Apr 11, 2026 Started: Jan 1, 2024 Primary completion: Sep 30, 2026 Completion: Sep 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on D-dimer and Diagnosis, this trial is actively recruiting participants. The trial is conducted by Canadian Institutes of Health Research (CIHR) and has accumulated 7 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Apr 2025 · 5 months · monthly snapshotRecruiting~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Apr 2026 · 10 months · monthly snapshotRecruitingApr 16, 2026 – present · 4 months · daily APIRecruiting

Change History

7 versions recorded
  1. Apr 16, 2026 — Present [daily]

    Recruiting

  2. Jun 2025 — Apr 2026 [monthly]

    Recruiting

  3. Apr 2025 — Jun 2025 [monthly]

    Recruiting

  4. Nov 2024 — Apr 2025 [monthly]

    Recruiting

  5. Sep 2024 — Nov 2024 [monthly]

    Recruiting

Show 2 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  2. Apr 2024 — Jul 2024 [monthly]

    Recruiting

    First recorded

Jan 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

It is important to diagnose pulmonary embolism in a timely manner to prevent death and long-term disability. More than half a million people (4-5% of emergency department patients) are tested for pulmonary embolism, although the positive rate is low. Imaging for PE testing exposes patients to radiation, is expensive, adds time to the emergency visit, and can lead to a false positive diagnoses. Existing protocols aimed at reducing unnecessary pulmonary embolism imaging are complex and seldom used by emergency physicians. Too many patients undergo unnecessary pulmonary embolism imaging. A new tool (called Adjust-Unlikely) could safely reduce pulmonary embolism imaging in Canada. A research group composed of researchers, emergency physicians, and patients developed the Adjust-Unlikely clinical decision rule: a rule which has been customized for emergency physicians and emergency patients. Adjust-Unlikely is highly sensitive at the bedside, meaning there are very few false negative results. The study aim is to prospectively validate Adjust-Unlikely pulmonary embolism testing in emergency patients with suspected pulmonary embolism.

Contact Information

Sponsor contact:
  • Canadian Institutes of Health Research (CIHR)
  • Dr. Kerstin de Wit
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations