deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT06435845

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

A Phase 2, Multicenter, Open-label Study to Evaluate the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Sponsor: Rallybio

Updated 10 times since 2024 Last updated: Mar 3, 2026 Started: Nov 21, 2024 Primary completion: Oct 1, 2025 Completion: Oct 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This study was terminated early by the sponsor due to insufficient drug exposure to achieve the intended therapeutic effect.

Listed as NCT06435845, this PHASE2 trial focuses on Fetal and Neonatal Alloimmune Thrombocytopenia and remains terminated or withdrawn. Sponsored by Rallybio, it has been updated 10 times since 2024, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotNot Yet Recruiting~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshotRecruiting~Feb 2025 – ~May 2025 · 3 months · monthly snapshotRecruiting~May 2025 – ~Jul 2025 · 2 months · monthly snapshotActive Not Recruiting~Jul 2025 – ~Dec 2025 · 5 months · monthly snapshotActive Not Recruiting~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshotActive Not Recruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshotTerminated~Mar 2026 – present · 5 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Mar 2026 — Present [monthly]

    Terminated PHASE2

  2. Feb 2026 — Mar 2026 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  3. Dec 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE2

  5. May 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 5 earlier versions
  1. Feb 2025 — May 2025 [monthly]

    Recruiting PHASE2

  2. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Sep 2024 — Jan 2025 [monthly]

    Not Yet Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE2

  5. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Rallybio
Data source: Rallybio

For direct contact, visit the study record on ClinicalTrials.gov .