deltatrials
Recruiting PHASE1 NCT06436742

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

A Phase 1b, Double-Blinded, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Efficacy of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes

Sponsor: argenx

Interventions ARGX-119 Placebo
Updated 9 times since 2024 Last updated: Feb 4, 2026 Started: Sep 24, 2024 Primary completion: Aug 24, 2027 Completion: Jan 24, 2028

Listed as NCT06436742, this PHASE1 trial focuses on CMS and Congenital Myasthenic Syndrome and remains actively recruiting participants. Sponsored by argenx, it has been updated 9 times since 2024, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Change History

9 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE1

    Status: Active Not RecruitingRecruiting

  2. Nov 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE1

  5. Dec 2024 — Feb 2025 [monthly]

    Recruiting PHASE1

Show 4 earlier versions
  1. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  2. Sep 2024 — Nov 2024 [monthly]

    Not Yet Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE1

  4. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • argenx
Data source: argenx

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

  • Belfast, United Kingdom
  • Chicago, United States
  • Marseille, France
  • Milan, Italy
  • Ottawa, Canada
  • Oxford, United Kingdom
  • Paris, France
  • Sacramento, United States
  • Valencia, Spain