deltatrials
Terminated EARLY_PHASE1 INTERVENTIONAL 1-arm NCT06462144

IMPT-514 in Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy

An Exploartory Trial of IMPT-514, An Autologous Anti-CD19/20 CAR T Therapy in Participants With Active, Refractory Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Conditions ANCA Associated Vasculitis (AAV) Idiopathic Inflammatory Myopathy (IIM) Systemic Lupus Erythematosus (SLE)
Interventions IMPT-514 CART Cell Injection
Updated 5 times since 2024 Last updated: Jan 26, 2026 Started: Jun 13, 2024 Primary completion: Oct 21, 2025 Completion: Oct 21, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The collaborating party has adjusted its R\&D strategy and terminated the study.

This EARLY_PHASE1 trial investigates ANCA Associated Vasculitis (AAV) and Idiopathic Inflammatory Myopathy (IIM) and is currently terminated or withdrawn. The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School leads this study, which shows 5 recorded versions since 2024 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotRecruiting~Dec 2024 – ~Feb 2026 · 14 months · monthly snapshotRecruiting~Feb 2026 – present · 6 months · monthly snapshotTerminated

Change History

5 versions recorded

  1. Feb 2026 — Present [monthly]

    Terminated EARLY_PHASE1

    Status: Recruiting → Terminated

  2. Dec 2024 — Feb 2026 [monthly]

    Recruiting EARLY_PHASE1

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting EARLY_PHASE1

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet Recruiting → Recruiting

  5. Jul 2024 — Aug 2024 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Jun 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Data source: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations