deltatrials
Recruiting INTERVENTIONAL NCT06619327

Resilient Together for Dementia (RT-D) (RT-D)

Resilient Together for Dementia: A Live Video Resiliency Dyadic Intervention for Persons With Dementia and Their Care-partners Early After Diagnosis

Sponsor: Icahn School of Medicine at Mount Sinai

Conditions Dementia
Updated 3 times since 2024 Last updated: Apr 11, 2026 Started: Feb 19, 2025 Primary completion: Aug 30, 2026 Completion: Jun 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Dementia, this trial is actively recruiting participants. The trial is conducted by Icahn School of Medicine at Mount Sinai and has accumulated 3 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Study Description(click to expand)

Both persons living with dementia and their spousal care-partners experience high levels of clinically elevated emotional distress, which can become chronic without treatment and negatively impact the health, quality of life, communication, and care-planning of both partners. A tailored dyadic intervention, such as the proposed Resilient Together for Dementia, delivered over live video to this at risk population has the potential to prevent chronic emotional distress and preserve quality of life for PWDs and their loved ones. A pilot feasibility randomized control trial (RCT; Aim 3; NIA Stage 1B; N=50 dyads) will be conducted of the refined RT-D versus a minimally enhanced educational control (MEUC, educational pamphlet). Primary outcomes will be feasibility, credibility, and acceptability markers to inform a hybrid efficacy effectiveness R01 (year 4) of RT-D vs. MEUC (NIA Stage II). In this subsequent R01, the researcher will examine RT-D's impact on emotional distress and quality of life outcomes and test mechanisms of change (individual and interpersonal resiliency skills) through mediation and moderation. The researcher will revise the approach if feasibility benchmarks are not met.

Both persons living with dementia and their spousal care-partners experience high levels of clinically elevated emotional distress, which can become chronic without treatment and negatively impact the health, quality of life, communication, and care-planning of both partners. A tailored dyadic intervention, such as the proposed Resilient Together for Dementia, delivered over live video to this at risk population has the potential to prevent chronic emotional distress and preserve quality of life for PWDs and their loved ones.

A pilot feasibility randomized control trial (RCT; Aim 3; NIA Stage 1B; N=50 dyads) will be conducted of the refined RT-D versus a minimally enhanced educational control (MEUC, educational pamphlet). Primary outcomes will be feasibility, credibility, and acceptability markers to inform a hybrid efficacy effectiveness R01 (year 4) of RT-D vs. MEUC (NIA Stage II). In this subsequent R01, the researcher will examine RT-D's impact on emotional distress and quality of life outcomes and test mechanisms of change (individual and interpersonal resiliency skills) through mediation and moderation. The researcher will revise the approach if feasibility benchmarks are not met.

Status Flow

~Oct 2024 – ~Apr 2025 · 6 months · monthly snapshotNot Yet Recruiting~Apr 2025 – ~Apr 2026 · 12 months · monthly snapshotRecruitingApr 16, 2026 – present · 4 months · daily APIRecruiting

Change History

3 versions recorded
  1. Apr 16, 2026 — Present [daily]

    Recruiting

    Phase: NANone

  2. Apr 2025 — Apr 2026 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  3. Oct 2024 — Apr 2025 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

This study will evaluate the feasibility and preliminary efficacy of the novel Resilient Together for Dementia (RT-D) intervention for couples following dementia diagnoses. The primary target is emotional distress, and the program aims to prevent chronic distress in at-risk couples.

Contact Information

Sponsor contact:
  • Icahn School of Medicine at Mount Sinai
  • National Institute on Aging (NIA)
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations