deltatrials
Recruiting NA INTERVENTIONAL 2-arm NCT06620185

GEneRating Mucosal Immunity After INfluenzA Infection and Vaccination in Lung and Lymphoid TissuE (GERMINATE)

A Two-arm, Non-randomised, Open-label Experimental Medicine Study to Compare Immune Responses Between Healthy Volunteers Aged 18-40years Receiving Either an Intranasal Live-attenuated Influenza Vaccine or Viral Challenge With GMP Influenza A/Belgium/4217/2015 (H3N2)

Sponsor: Imperial College Healthcare NHS Trust

Conditions Influenza
Interventions FLUENZ Influenza challenge virus
Updated 2 times since 2024 Last updated: Apr 30, 2025 Started: Apr 16, 2025 Primary completion: Jan 6, 2026 Completion: Jan 6, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Influenza, this trial is actively recruiting participants. The trial is conducted by Imperial College Healthcare NHS Trust and has accumulated 2 data snapshots since 2025. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Oct 2024 – ~Jun 2025 · 8 months · monthly snapshotNot Yet Recruiting~Jun 2025 – present · 15 months · monthly snapshotRecruiting

Change History

2 versions recorded

  1. Jun 2025 — Present [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  2. Oct 2024 — Jun 2025 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Imperial College Healthcare NHS Trust
  • Imperial College London
Data source: Imperial College London

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations