deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06717438

Study of Zatolmilast (BPN14770) in Participants With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome [JS])

A Phase 2 Randomized, Double-blind, Placebo-controlled, Study of Zatolmilast (BPN14770) in Subjects With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome)

Sponsor: Shionogi

Interventions BPN14770 Placebo
Updated 5 times since 2025 Last updated: Jan 16, 2026 Started: May 13, 2025 Primary completion: Jan 31, 2030 Completion: Jan 31, 2030
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Jordan's Syndrome and PPP2R5D Neurodevelopmental Disorder and is currently ongoing. Shionogi leads this study, which shows 5 recorded versions since 2025 — indicating limited longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshotNot Yet Recruiting~Apr 2025 – ~Aug 2025 · 4 months · monthly snapshotNot Yet Recruiting~Aug 2025 – ~Feb 2026 · 6 months · monthly snapshotEnrolling By Invitation~Feb 2026 – present · 5 months · monthly snapshotActive Not Recruiting

Change History

5 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

    Status: Enrolling By InvitationActive Not Recruiting

  2. Aug 2025 — Feb 2026 [monthly]

    Enrolling By Invitation PHASE2

    Status: Not Yet RecruitingEnrolling By Invitation

  3. Apr 2025 — Aug 2025 [monthly]

    Not Yet Recruiting PHASE2

  4. Feb 2025 — Apr 2025 [monthly]

    Not Yet Recruiting PHASE2

  5. Jan 2025 — Feb 2025 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shionogi
Data source: Shionogi Inc.

For direct contact, visit the study record on ClinicalTrials.gov .