Recruiting OBSERVATIONAL NCT06747117

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II) (STRIDE II)

STRIDE II: A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System II

Sponsor: Penumbra Inc.

Conditions LE ALI Lower Extremity Acute Limb Ischemia

Interventions Indigo Aspiration System

Updated 8 times since 2025 Last updated: Apr 24, 2026 Started: May 18, 2025 Primary completion: Jun 1, 2028 Completion: Jan 1, 2029

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates LE ALI and Lower Extremity Acute Limb Ischemia and is currently actively recruiting participants. Penumbra Inc. leads this study, which shows 8 recorded versions since 2025 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Apr 28, 2026 — Present [daily]

Recruiting
Mar 2026 — Apr 2026 [monthly]

Recruiting
Feb 2026 — Mar 2026 [monthly]

Recruiting
Jan 2026 — Feb 2026 [monthly]

Recruiting
Dec 2025 — Jan 2026 [monthly]

Recruiting

▶ Show 3 earlier versions

Aug 2025 — Dec 2025 [monthly]

Recruiting
Jul 2025 — Aug 2025 [monthly]

Recruiting

Status: Not Yet Recruiting → Recruiting
Jan 2025 — Jul 2025 [monthly]

Not Yet Recruiting

First recorded

Eligibility Summary

The primary objective of this study is to collect and evaluate clinical evidence supporting the safety and performance of the Indigo™ Aspiration System in a patient population with lower extremity acute limb ischemia (LE ALI).

Contact Information

Sponsor contact:

Penumbra Inc.

Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Aurora, United States , Baltimore, United States , Bedford Park, Australia , Bradenton, United States , Brescia, Italy , Cincinnati, United States , Cleveland, United States , Concord, United States , Gainesville, United States and 23 more locations