Recruiting PHASE1 INTERVENTIONAL 2-arm NCT06747390

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery (856397)

A Phase I Randomized Controlled Trial of Intratumoral Lidocaine Injection Before Transoral Robotic Surgery (TORS) and Neck Dissection for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Sponsor: Ryan Carey

Conditions Human Papilloma Virus Oropharyngeal Cancer Oropharyngeal Squamous Cell Carcinoma (OPSCCA) Squamous Cell Carcinoma

Interventions Lidocaine 1% Injectable Solution

Updated 3 times since 2025 Last updated: Apr 27, 2025 Started: Apr 23, 2025 Primary completion: Nov 1, 2026 Completion: Nov 1, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Human Papilloma Virus and Oropharyngeal Cancer and is currently actively recruiting participants. Ryan Carey leads this study, which shows 3 recorded versions since 2025 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

3 versions recorded

May 2025 — Present [monthly]

Recruiting PHASE1
Feb 2025 — May 2025 [monthly]

Recruiting PHASE1

Status: Not Yet Recruiting → Recruiting
Jan 2025 — Feb 2025 [monthly]

Not Yet Recruiting PHASE1

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ryan Carey

Data source: Abramson Cancer Center at Penn Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Philadelphia, United States