deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT06897358

Leniolisib for Immune Dysregulation in CVID

A Study to Assess Safety and Tolerability, and Explore Efficacy of Leniolisib for Immune Dysregulation in Common Variable Immunodeficiency (CVID)

Sponsor: Lahey Hospital & Medical Center

Interventions Leniolisib
Updated 6 times since 2025 Last updated: Feb 10, 2026 Started: Feb 12, 2025 Primary completion: Oct 31, 2026 Completion: Oct 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Common Variable Immunodeficiency (CVID), this trial is ongoing. The trial is conducted by Lahey Hospital & Medical Center and has accumulated 6 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Aug 2025 · 3 months · monthly snapshotRecruiting~Aug 2025 – ~Oct 2025 · 2 months · monthly snapshotRecruiting~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotActive Not Recruiting

Change History

6 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Nov 2025 — Feb 2026 [monthly]

    Recruiting PHASE2

  3. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  4. Aug 2025 — Oct 2025 [monthly]

    Recruiting PHASE2

  5. May 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

Show 1 earlier version
  1. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE2

    First recorded

Feb 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Lahey Hospital & Medical Center
  • Pharming Technologies B.V.
Data source: Pharming Technologies B.V.

For direct contact, visit the study record on ClinicalTrials.gov .