deltatrials
Recruiting INTERVENTIONAL NCT06908447

Cold Water and Decision-Making (CoVa)

Voluntary Cold-Water Immersion Effects on Value-Based Choice

Sponsor: German Institute of Human Nutrition

Updated 3 times since 2025 Last updated: Apr 17, 2026 Started: Aug 28, 2025 Primary completion: Dec 31, 2026 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06908447, this observational or N/A phase trial focuses on Behavior and Psychological Wellbeing and remains actively recruiting participants. Sponsored by German Institute of Human Nutrition, it has been updated 3 times since 2025, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Study Description(click to expand)

This randomized within-subject cross-over design behavioral study in cognitive neuroscience will employ an acute peripheral physiological intervention, i.e., a 10-minute full-body cold-water (10-16°C) immersion vs. a control condition (10 min @ 30- 36°C water) on two visits separated by approx. 30 days. Forty eligible female and male participants will be subject to a head-out full-body cold-water immersion or a warm-water condition (control) on two visits. Participants will perform resting-state and task-based non-invasive electrophysiological recordings of the heart, pulse, respiration, skin conductance, and pupil, will undergo thermographic imaging, pre- and post-immersion blood sampling (4 time points), engage in two computer-based decision-making tasks (reinforcement learning task, risk decision-making task), a brief food choice task, and receive a battery of psychometric questionnaires. The visits are separated by approximately 30 days and do not differ in their timeline except for the primary intervention, i.e., cold vs warm-water immersion, and the medical screening on visit 1.

This randomized within-subject cross-over design behavioral study in cognitive neuroscience will employ an acute peripheral physiological intervention, i.e., a 10-minute full-body cold-water (10-16°C) immersion vs. a control condition (10 min @ 30- 36°C water) on two visits separated by approx. 30 days.

Forty eligible female and male participants will be subject to a head-out full-body cold-water immersion or a warm-water condition (control) on two visits. Participants will perform resting-state and task-based non-invasive electrophysiological recordings of the heart, pulse, respiration, skin conductance, and pupil, will undergo thermographic imaging, pre- and post-immersion blood sampling (4 time points), engage in two computer-based decision-making tasks (reinforcement learning task, risk decision-making task), a brief food choice task, and receive a battery of psychometric questionnaires. The visits are separated by approximately 30 days and do not differ in their timeline except for the primary intervention, i.e., cold vs warm-water immersion, and the medical screening on visit 1.

Status Flow

~May 2025 – ~Oct 2025 · 5 months · monthly snapshotNot Yet Recruiting~Oct 2025 – ~Apr 2026 · 7 months · monthly snapshotRecruitingApr 21, 2026 – present · 2 months · daily APIRecruiting

Change History

3 versions recorded
  1. Apr 21, 2026 — Present [daily]

    Recruiting

    Phase: NANone

  2. Oct 2025 — Apr 2026 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  3. May 2025 — Oct 2025 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

The behavioral within-subject cross-over design study "CoVa" aims to investigate the effect of a short-term full-body cold-water immersion vs. warm-water immersion control on value-based choice, psychological well-being, and peripheral physiology.

Contact Information

Sponsor contact:
  • German Institute of Human Nutrition
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations