deltatrials
Recruiting INTERVENTIONAL NCT06925737

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

A Phase 3, Open-label Study of Ifinatamab Deruxtecan Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (IDeate-Prostate01)

Sponsor: Daiichi Sankyo

Updated 10 times since 2025 Last updated: Apr 24, 2026 Started: May 13, 2025 Primary completion: Jun 26, 2028 Completion: Jan 6, 2031
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Prostate Cancer and Prostatic Neoplasms and is currently actively recruiting participants. Daiichi Sankyo leads this study, which shows 10 recorded versions since 2025 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshotRecruiting~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Jan 2026 · 2 months · monthly snapshotRecruiting~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – ~May 2026 · 2 months · monthly snapshotRecruitingMay 4, 2026 – present · 3 months · daily APIRecruiting

Change History

10 versions recorded
  1. May 4, 2026 — Present [daily]

    Recruiting

    Phase: PHASE3None

  2. Mar 2026 — May 2026 [monthly]

    Recruiting PHASE3

  3. Feb 2026 — Mar 2026 [monthly]

    Recruiting PHASE3

  4. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE3

  5. Nov 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

Show 5 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

  3. Jul 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  4. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  5. May 2025 — Jun 2025 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-2400) to treat mCRPC. The goal of this study is to learn if people who receive I-DXd live longer overall and live longer without the cancer growing or spreading than people who receive chemotherapy.

Contact Information

Sponsor contact:
  • Daiichi Sankyo
  • Merck Sharp & Dohme LLC
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .