Not Yet Recruiting PHASE4 INTERVENTIONAL 3-arm NCT06936709

Perioperative Colchicine for TKA

Effect of Colchicine in the Perioperative Period on Reducing Post-Operative Pain in Total Knee Arthroplasty

Sponsor: Geisinger Clinic

Conditions Osteoarthritis of Knee Perioperative Pain Control Recovery Following Primary Total Knee Arthroplasty

Interventions Colchicine 1.8 mg (loading dose) + Dextrose Oral Placebo Colchicine 1.8 mg + 0.6 mg Dextrose Oral Placebo

Updated 2 times since 2025 Last updated: Aug 15, 2025 Started: Dec 1, 2025 Primary completion: Jan 1, 2026 Completion: Mar 1, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Osteoarthritis of Knee and Perioperative Pain Control, this trial is actively recruiting participants. The trial is conducted by Geisinger Clinic and has accumulated 2 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

2 versions recorded

Sep 2025 — Present [monthly]

Not Yet Recruiting PHASE4
May 2025 — Sep 2025 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Geisinger Clinic
St. Luke's Hospital, Kansas City, Missouri

Data source: Geisinger Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.