Recruiting PHASE1 INTERVENTIONAL 1-arm NCT07065409

Treatment of Moyamoya Disease With iPSC-derived Exosomes

Phase I Clinical Trial of Induced Pluripotent Stem Cell-derived Extracellular Vesicles Combined With Temporal Muscle Flap Application in Promoting Intracranial and Extracranial Blood Flow Reconstruction in Patients With Moyamoya Disease

Sponsor: Huaqiu Zhang

Conditions Moyamoya Disease

Interventions iPSC-EVs

Updated 2 times since 2025 Last updated: Sep 29, 2025 Started: May 26, 2025 Primary completion: May 31, 2026 Completion: Oct 31, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Moyamoya Disease, this trial is actively recruiting participants. The trial is conducted by Huaqiu Zhang and has accumulated 2 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

2 versions recorded

Nov 2025 — Present [monthly]

Recruiting PHASE1
Aug 2025 — Nov 2025 [monthly]

Recruiting PHASE1

First recorded

May 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Huaqiu Zhang

Data source: Tongji Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Wuhan, China