Recruiting PHASE4 INTERVENTIONAL 4-arm NCT07131592

Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

The Effect of Tranexamic Acid on Drainage Volume and Time to Drain Removal in Reduction Mammaplasty Patients

Sponsor: Massachusetts General Hospital

Conditions Breast Reductions Drain Output After Breast Reduction Surgery

Interventions IV TXA Topical TXA Topical saline

Updated 3 times since 2025 Last updated: Jan 14, 2026 Started: Nov 18, 2025 Primary completion: Mar 1, 2027 Completion: Aug 31, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Breast Reductions and Drain Output After Breast Reduction Surgery, this trial is actively recruiting participants. The trial is conducted by Massachusetts General Hospital and has accumulated 3 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

3 versions recorded

Feb 2026 — Present [monthly]

Recruiting PHASE4

Status: Not Yet Recruiting → Recruiting
Nov 2025 — Feb 2026 [monthly]

Not Yet Recruiting PHASE4
Sep 2025 — Nov 2025 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Massachusetts General Hospital

Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Boston, United States