Recruiting PHASE1 INTERVENTIONAL 1-arm
NCT07179328
Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy
Assessment of Safety and Feasibility of Focused Ultrasound Next Generational Dome Helmet Mediated Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy
Sponsor: Sunnybrook Health Sciences Centre
Conditions
Brain Tumor Adult Brain Tumor, Primary GBM Glioblastoma Multiforme (GBM) Glioblastoma Multiforme Glioma Glioblastoma Multiforme of Brain Glioma HGG
Interventions
Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension Focused Ultrasound Next Generation Dome Helmet
Updated 1 time since 2025 Last updated: Sep 10, 2025 Started: Jun 4, 2025 Primary completion: Jul 31, 2027 Completion: Nov 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.
A PHASE1 clinical study on Brain Tumor Adult and Brain Tumor, Primary, this trial is actively recruiting participants. The trial is conducted by Sunnybrook Health Sciences Centre and has accumulated 1 data snapshot since 2025. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
1 version recorded Recruiting — PHASE1
[monthly]
Eligibility Summary
No eligibility information available.
Contact Information
Sponsor contact:
- Sunnybrook Health Sciences Centre
Data source: Sunnybrook Health Sciences Centre
For direct contact, visit the study record on ClinicalTrials.gov .