deltatrials
Recruiting PHASE4 INTERVENTIONAL 1-arm NCT07189377

Combined Light, ExVivo, and Antivirals for Recipients of Lungs From HBV Donors (CLEAR-HBV)

Lung Transplantation Using Hepatitis B Positive Donors to Hepatitis B Negative Recipients Using Ex-Vivo Treatment of Organs: A Safety Trial

Sponsor: University Health Network, Toronto

Conditions Hepatitis B Virus (HBV) Lung Transplant Recipient
Interventions EVLP UV Light Treatment Entecavir HBIG
Updated 2 times since 2025 Last updated: Nov 13, 2025 Started: Sep 24, 2025 Primary completion: Aug 31, 2027 Completion: Aug 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Hepatitis B Virus (HBV) and Lung Transplant Recipient and is currently actively recruiting participants. University Health Network, Toronto leads this study, which shows 2 recorded versions since 2025 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Oct 2025 – ~Dec 2025 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2025 – present · 7 months · monthly snapshotRecruiting

Change History

2 versions recorded

  1. Dec 2025 — Present [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  2. Oct 2025 — Dec 2025 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Sep 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Health Network, Toronto
Data source: University Health Network, Toronto

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations