A Study to Assess the Genetic Variations in Bile Flow Disorders: Linking Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes to Symptoms in Adults With Recurrent Cholestasis in Spain (REGENIC)
Characterization of Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes in Adult Patients With Idiopathic Recurrent and Chronic Cholestasis in Spain - REGENIC
Sponsor: Ipsen
Listed as NCT07191704, this observational or N/A phase trial focuses on PFIC - Progressive Familial Intrahepatic Cholestasis and remains actively recruiting participants. Sponsored by Ipsen, it has been updated 5 times since 2025, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
5 versions recorded-
May 4, 2026 — Present [daily]
Recruiting
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Mar 2026 — May 2026 [monthly]
Recruiting
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Feb 2026 — Mar 2026 [monthly]
Recruiting
Status: Not Yet Recruiting → Recruiting
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Jan 2026 — Feb 2026 [monthly]
Not Yet Recruiting
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Oct 2025 — Jan 2026 [monthly]
Not Yet Recruiting
First recorded
Eligibility Summary
Progressive Familial Intrahepatic Cholestasis (PFIC) is a group of inherited conditions that affect how bile moves in the liver, which can lead to serious liver problems. Doctors usually recommend genetic testing for patients with unexplained bile issues-after ruling out more common causes-to better understand the problem. However, there isn't much information on how common these genetic changes are in adults with these liver issues, especially in Spain. This study will observe these genetic changes so that doctors can diagnose the condition more clearly and create personalized treatment plans. This study will be conducted in several centers across Spain for 10 months. Each adult participant will take part in a single-day visit where their health information will be collected, and a blood sample will be taken for both routine tests and genetic analysis.
Contact Information
- Ipsen
For direct contact, visit the study record on ClinicalTrials.gov .