Recruiting PHASE3 INTERVENTIONAL 2-arm NCT07200180

Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery

Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery (PAIRS Trial)

Sponsor: Negovsky Reanimatology Research Institute

Conditions Carotid Artery Disease Carotid Artery Stenoses

Interventions Nitrogen-oxygen breathing mixture Аrgon-oxygen breathing mixture

Updated 2 times since 2025 Last updated: Dec 26, 2025 Started: Sep 22, 2025 Primary completion: Oct 1, 2026 Completion: Nov 1, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Carotid Artery Disease and Carotid Artery Stenoses and is currently actively recruiting participants. Negovsky Reanimatology Research Institute leads this study, which shows 2 recorded versions since 2025 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

2 versions recorded

Jan 2026 — Present [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Oct 2025 — Jan 2026 [monthly]

Not Yet Recruiting PHASE3

First recorded

Sep 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Negovsky Reanimatology Research Institute

Data source: Negovsky Reanimatology Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Moscow, Russia