deltatrials
Recruiting INTERVENTIONAL NCT07219173

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

A Phase 2, Multicenter, Randomized, Double-blind, 52-week Study, to Investigate the Efficacy and Safety of Brenipatide Compared With Placebo for the Treatment of Adult Participants With Uncontrolled Moderate to Severe Asthma

Sponsor: Eli Lilly and Company

Conditions Asthma
Updated 6 times since 2025 Last updated: Apr 16, 2026 Started: Oct 22, 2025 Primary completion: Apr 1, 2028 Completion: Jun 1, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Asthma and is currently actively recruiting participants. Eli Lilly and Company leads this study, which shows 6 recorded versions since 2025 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshotRecruiting~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshotRecruiting~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshotRecruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshotRecruiting~Mar 2026 – ~Apr 2026 · 48 days · monthly snapshotRecruitingApr 18, 2026 – present · 4 months · daily APIRecruiting

Change History

6 versions recorded
  1. Apr 18, 2026 — Present [daily]

    Recruiting

    Phase: PHASE2None

  2. Mar 2026 — Apr 2026 [monthly]

    Recruiting PHASE2

  3. Feb 2026 — Mar 2026 [monthly]

    Recruiting PHASE2

  4. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE2

  5. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

Show 1 earlier version
  1. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE2

    First recorded

Oct 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .