deltatrials
Recruiting INTERVENTIONAL NCT07226349

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

A Phase 1a/1b, Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BG-75098 Alone and in Combination With Other Agents in Patients With Advanced Solid Tumors

Sponsor: BeOne Medicines

Updated 5 times since 2025 Last updated: Apr 14, 2026 Started: Dec 11, 2025 Primary completion: Nov 1, 2028 Completion: Nov 1, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Advanced Solid Tumor and is currently actively recruiting participants. BeOne Medicines leads this study, which shows 5 recorded versions since 2025 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Study Description(click to expand)

This study will be conducted in 2 phases: Phase 1a Dose Escalation and Phase 1b Dose Expansion.

This study will be conducted in 2 phases: Phase 1a Dose Escalation and Phase 1b Dose Expansion.

Status Flow

~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshotRecruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshotRecruiting~Mar 2026 – ~Apr 2026 · 46 days · monthly snapshotRecruitingApr 16, 2026 – present · 2 months · daily APIRecruiting

Change History

5 versions recorded
  1. Apr 16, 2026 — Present [daily]

    Recruiting

    Phase: PHASE1None

  2. Mar 2026 — Apr 2026 [monthly]

    Recruiting PHASE1

  3. Feb 2026 — Mar 2026 [monthly]

    Recruiting PHASE1

  4. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Dec 2025 — Jan 2026 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75098 alone and in combination with BGB-43395 and fulvestrant in participants with advanced solid tumors.

Contact Information

Sponsor contact:
  • BeOne Medicines
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .