Recruiting NA INTERVENTIONAL 2-arm NCT07286578

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium

Sponsor: Fundación EPIC

Conditions Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Artery Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Interventions CT(Computed Tomography) guided Percutaneous Coronary Intervention IVUS (Intravascular Ultrasound) guided Percutaneous Coronary Intervention

Updated 2 times since 2026 Last updated: Feb 9, 2026 Started: Dec 22, 2025 Primary completion: Dec 15, 2029 Completion: Jan 1, 2030

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Arterial Occlusive Diseases and Arteriosclerosis, this trial is actively recruiting participants. The trial is conducted by Fundación EPIC and has accumulated 2 data snapshots since 2025. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

2 versions recorded

Feb 2026 — Present [monthly]

Recruiting NA
Jan 2026 — Feb 2026 [monthly]

Recruiting NA

First recorded

Dec 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Fundación EPIC

Data source: Fundación EPIC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barcelona, Spain , Boston, United States , Jersey City, United States , Leicester, United Kingdom , León, Spain , London, United Kingdom , Madrid, Spain , Minneapolis, United States , New York, United States , Newcastle, United Kingdom and 1 more location