Active Not Recruiting PHASE4 INTERVENTIONAL 3-arm NCT07401745

Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular Disorders (TMD)

Combination Treatment of Occlusal Splint Appliance and Granisetron Injection Into the Masseter Muscle for Management of Myofascial Pain Related to Temporomandibular Disorders: A Randomized Controlled Parallel-arm Clinical Trial

Sponsor: Mansoura University

Conditions TMD TMD/Orofacial Pain Temporomandibular Disorder (TMD)

Interventions Granisetron lidocaine occlusal splint

Updated 2 times since 2026 Last updated: Mar 3, 2026 Started: Jan 27, 2026 Primary completion: Jul 31, 2026 Completion: Jul 31, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on TMD and TMD/Orofacial Pain, this trial is ongoing. The trial is conducted by Mansoura University and has accumulated 2 data snapshots since 2026. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

2 versions recorded

Mar 2026 — Present [monthly]

Active Not Recruiting PHASE4

Status: Recruiting → Active Not Recruiting
Feb 2026 — Mar 2026 [monthly]

Recruiting PHASE4

First recorded

Jan 2026

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Mansoura University

Data source: Mansoura University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Al Mansurah, Egypt