deltatrials
Recruiting INTERVENTIONAL NCT07446192

Magnetoencephalography (MEG) Pilot Study (MEG)

Network Characteristics in Essential Tremor (ET) Patients Undergoing High-Intensity Focused Ultrasound (HiFU): a Magnetoencephalography (MEG) Pilot Study

Sponsor: University of Florida

Conditions Essential Tremor
Interventions Clinical evaluations MEG MRI and fMRI scans Questionnaires and rating scales that Sensor-based motor assessments
Updated 2 times since 2026 Last updated: Apr 27, 2026 Started: Feb 17, 2026 Primary completion: Aug 1, 2027 Completion: Aug 1, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Essential Tremor and is currently actively recruiting participants. University of Florida leads this study, which shows 2 recorded versions since 2026 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Study Description(click to expand)

Participation in this study will last for approximately eight months. Participants will be asked to attend a total of six study visits. These include a screening visit to see if a potential participant qualifies for the study, an assessment visit before treatment and treatment visits. Prior to and after treatment (one day, six weeks, and six months after treatment), participants will have Magnetoencephalography (MEG), Functional Magnetic Resonance Imaging (fMRI), Sensor-Based Gait and Motor Function Assessments and Self-Report Questionnaires.

Participation in this study will last for approximately eight months. Participants will be asked to attend a total of six study visits. These include a screening visit to see if a potential participant qualifies for the study, an assessment visit before treatment and treatment visits. Prior to and after treatment (one day, six weeks, and six months after treatment), participants will have Magnetoencephalography (MEG), Functional Magnetic Resonance Imaging (fMRI), Sensor-Based Gait and Motor Function Assessments and Self-Report Questionnaires.

Status Flow

~Mar 2026 – ~May 2026 · 2 months · monthly snapshotNot Yet RecruitingMay 4, 2026 – present · 57 days · daily APIRecruiting

Change History

2 versions recorded

  1. May 4, 2026 — Present [daily]

    Recruiting

    Status: Not Yet Recruiting → Recruiting · Phase: NA → None

  2. Mar 2026 — May 2026 [monthly]

    Not Yet Recruiting NA

    First recorded

Feb 2026

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

The purpose of this research is to learn more about how the brain works in people with essential tremor, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). Essential tremor is a movement disorder that causes shaking, usually in the hands, and can make everyday tasks difficult. HiFU is a treatment that uses focused sound waves to target a small area in the brain involved in tremor. In this study, the investigators aim to understand how this treatment affects the brain's networks by using safe, non-invasive tests such as brain imaging, brain wave recordings, and movement assessments.

Contact Information

Sponsor contact:
  • University of Florida
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations