deltatrials
Completed INTERVENTIONAL NCT07554170

Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in PSVT

Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in Supraventricular Tachycardia: A Randomized Clinical Trial

Sponsor: Hormozgan University of Medical Sciences

Conditions PSVT SVT Supraventricular Arrhythmia Supraventricular Tachycardia Supraventricular Tachycardias
Interventions Double Syringe Adenosine Single-syringe Adenosine
Updated 1 time since 2026 Last updated: Apr 23, 2026 Started: May 21, 2024 Primary completion: Dec 21, 2025 Completion: Dec 21, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT07554170, this observational or N/A phase trial focuses on PSVT and SVT and remains completed. Sponsored by Hormozgan University of Medical Sciences, it has been updated 1 time since 2024, reflecting limited change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Study Description(click to expand)

The American Heart Association 2015 guidelines recommend adenosine for non-hypotensive patients with regular narrow complex SVT. Adenosine is usually given as a rapid intravenous bolus of 6mg over 1-2 seconds, followed by a 20ml saline flush. If the first dose does not result in the termination of SVT to normal sinus rhythm (NSR) within 1-2 minutes, a repeat dose of 12mg can be given, and the dose may be repeated one more time, if necessary, for a total of three doses. The double-syringe technique (DST) is the standard method for administering adenosine. However, recent studies suggest that the single-syringe technique (SST) may be simpler and potentially beneficial. This technique injects adenosine and saline simultaneously at the same time instead of two separate injections. The study aims to determine if the SST method is non-inferior to the DST method.

The American Heart Association 2015 guidelines recommend adenosine for non-hypotensive patients with regular narrow complex SVT. Adenosine is usually given as a rapid intravenous bolus of 6mg over 1-2 seconds, followed by a 20ml saline flush. If the first dose does not result in the termination of SVT to normal sinus rhythm (NSR) within 1-2 minutes, a repeat dose of 12mg can be given, and the dose may be repeated one more time, if necessary, for a total of three doses.

The double-syringe technique (DST) is the standard method for administering adenosine. However, recent studies suggest that the single-syringe technique (SST) may be simpler and potentially beneficial. This technique injects adenosine and saline simultaneously at the same time instead of two separate injections. The study aims to determine if the SST method is non-inferior to the DST method.

Status Flow

May 4, 2026 – present · 2 months · daily APICompleted

Change History

1 version recorded
Completed [daily]

Eligibility Summary

The purpose of the study is to compare the effectiveness of two different methods of administering adenosine for the treatment of stable supraventricular tachycardia (SVT).

Contact Information

Sponsor contact:
  • Hormozgan University of Medical Sciences
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations