Not Yet Recruiting INTERVENTIONAL NCT07560046

Combating Related Epidemics in HCV (CREST)

Combating Related Epidemics in HCV Through Simplified Testing and Treatment. A Cluster Randomized Trial of Point-of-care Hepatitis C Testing and Treatment Among Key Populations

Sponsor: Abbott

Conditions HEPATITIS C (HCV) HIV - Human Immunodeficiency Virus Hepatitis B Virus (HBV)

Interventions Abbott Determine HIV - 1/2 Ag/Ab Abbott Determine HbsAg 2 Cepheid GeneXpert HCV Test Sofosbuvir / Velpatasvir Oral Tablet [Epclusa]

Updated 1 time since 2026 Last updated: Apr 23, 2026 Started: Aug 1, 2026 Primary completion: Nov 30, 2030 Completion: Dec 30, 2030

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on HEPATITIS C (HCV) and HIV - Human Immunodeficiency Virus, this trial is actively recruiting participants. The trial is conducted by Abbott and has accumulated 1 data snapshot since 2026. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

Change History

1 version recorded

Not Yet Recruiting [daily]

Eligibility Summary

This is a two-arm cluster randomized control trial to evaluate the effectiveness of a single-visit point-of-care (POC) test and treat bundle (intervention arm) compared to the current standard-of-care (SOC, control arm). 1:1 randomization occurs at the site level.

Contact Information

Sponsor contact:

Abbott
Cepheid
Duke University
Flinders University International Centre for Point-of-care Testing
Gilead Sciences
Kirby Institute
National Institute of Allergy and Infectious Diseases (NIAID)
University of San Diego
West Virginia University
Yale University

Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.