National Institute of Mental Health (NIMH) Clinical Trials
Sponsors / National Institute of Mental Health (NIMH)
According to ClinicalTrials.gov, National Institute of Mental Health (NIMH) has served as lead sponsor on 1,836 registered trials. 258 trials are actively recruiting participants, 31 remain active without open enrollment, and 1354 have concluded. 75 of these trials ended early via termination or withdrawal. The most common reasons cited for termination include slow or insufficient recruitment, efficacy or futility findings. The cumulative planned enrollment figure across all listed trials is 1,270,254 participants. All figures are drawn directly from ClinicalTrials.gov and updated as sponsors submit revisions.
Termination reasons: Other51% · Recruitment27% · Efficacy8% · Funding7% · Safety4% · PI/or_Site3% · Regulatory1%
Recent Terminations
- Castration-Resistant Prostate Carcinoma"Slow accrual"
- Adolescent Depression"Terminated early due to concerns from the NIH DSMB regarding the rate of recruitment and the resulting inability to accomplish the initially approved study aims"
- Suicidal Ideation"Data Safety Monitoring Board (DSMB) recommendation per Charter stopping rules. The study surpassed the pre-planned futility boundary."
- Depression"due to low recruitment"
- Healthy"due to futility"
- Depression"Low recruitment"
- Multiple Sclerosis"due to futility"
- Attention Deficit Disorder"The study was terminated because our funding agency, the NIH, did not grant a no-cost extension to meet our recruitment goals."
- Anxiety"We were unable to obtain the intended sample size."
- Schizophrenia"Dr. Ralph Hoffman unexpectedly passed away."
Active Trials (31 total)
- NCT00001174
- NCT00001246
- NCT00018057
- NCT00025935
- NCT00271622
- NCT00397111
- NCT01132885
- NCT01617408
- NCT02531893
- NCT07169630
- NCT05669703
- NCT06176638
- NCT00001360
- NCT01087281
- NCT01266577
- NCT03388606
- NCT04639830
- NCT05282277
- NCT06462196
- NCT06484088