deltatrials
Completed PHASE3 NCT00001017

Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS

Comparison of Fluconazole (UK-49,858) and Amphotericin B for Maintenance Treatment of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions HIV Infections Meningitis, Cryptococcal
Interventions Amphotericin B Fluconazole
Updated 6 times since 2017 Last updated: Mar 11, 2011 Primary completion: Jul 31, 1991

This PHASE3 trial investigates HIV Infections and Meningitis, Cryptococcal and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 6 recorded versions since 2026 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Pfizer
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baltimore, United States, Boston, United States, Buffalo, United States, Chapel Hill, United States, Cincinnati, United States, Cleveland, United States, Columbus, United States, Durham, United States, Elmhurst, United States, Indianapolis, United States and 8 more location s