deltatrials
Completed PHASE3 NCT00002514

Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission

Phase III Randomized Trial of Autologous and Allogeneic Stem Cell Transplantation Versus Intensive Conventional Chemotherapy in Acute Lymphoblastic Leukemia in First Remission

Sponsor: Eastern Cooperative Oncology Group

Conditions Leukemia
Interventions allogeneic bone marrow transplantation asparaginase autologous bone marrow transplantation cyclophosphamide cytarabine daunorubicin hydrochloride dexamethasone etoposide imatinib mesylate leucovorin calcium mercaptopurine methotrexate peripheral blood stem cell transplantation prednisone radiation therapy sargramostim thioguanine vincristine sulfate
Updated 7 times since 2017 Last updated: Jun 14, 2023 Started: May 7, 1993 Primary completion: Dec 31, 2006

This PHASE3 trial investigates Leukemia and is currently completed. Eastern Cooperative Oncology Group leads this study, which shows 7 recorded versions since 1993 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Change History

7 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2023 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 2 earlier versions

  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

May 1993

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eastern Cooperative Oncology Group
  • Medical Research Council
  • National Cancer Institute (NCI)
Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States, Aurora, United States, Bemidji, United States, Boston, United States, Boulder, United States, Burnsville, United States, Canton, United States, Cedar Rapids, United States, Cincinnati, United States, Cleveland, United States and 55 more location s