Terminated PHASE3 INTERVENTIONAL NCT00002976

Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer

A Randomized Double-Blinded Trial of Estrogen Replacement Therapy Versus Placebo in Women With Stage I or II Endometrial Adenocarcinoma

Sponsor: Eastern Cooperative Oncology Group

Conditions Endometrial Cancer

Interventions conjugated estrogens

Updated 8 times since 2017 Last updated: Apr 10, 2013 Started: Jun 30, 1997 Primary completion: Jul 31, 2006

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was terminated. No reason was provided.

Other terminated trials from Eastern Cooperative Oncology Group

More terminations from Eastern Cooperative Oncology Group

Other Endometrial Cancer trials with similar outcome

Browse all Endometrial Cancer trials

This PHASE3 trial investigates Endometrial Cancer and is currently terminated or withdrawn. Eastern Cooperative Oncology Group leads this study, which shows 8 recorded versions since 1997 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Terminated PHASE3
Sep 2024 — Sep 2025 [monthly]

Terminated PHASE3
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE3
May 2023 — Jul 2024 [monthly]

Terminated PHASE3
Feb 2021 — May 2023 [monthly]

Terminated PHASE3

▶ Show 3 earlier versions

Jan 2021 — Feb 2021 [monthly]

Terminated PHASE3
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE3
Jan 2017 — Jun 2018 [monthly]

Terminated PHASE3

First recorded

Jun 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eastern Cooperative Oncology Group
Gynecologic Oncology Group
National Cancer Institute (NCI)
SWOG Cancer Research Network

Data source: GOG Foundation

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Abington, United States , Albany, United States , Albuquerque, United States , Ann Arbor, United States , Atlanta, United States , Baton Rouge, United States , Billings, United States , Biloxi, United States , Birmingham, United States , Boston, United States and 91 more locations